Inflammatory Response

The inflammatory response must be actively terminated when no longer needed to prevent unnecessary "bystander" damage to tissues. Failure to do so results in chronic inflammation, cellular destruction, and attempts to heal the inflamed tissue. One intrinsic mechanism employed to terminate inflammation is the short half-life of inflammatory mediators in vivo. They have a limited time frame to affect their target before breaking down into non-functional components, therefore constant inflammatory stimulation is needed to propagate their effects.

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Ihe Inflammatory Response can be triggered by invasion of bacteria,Substances released by bacteiria by damaged cells accumulate in tissue small blood vessels become more premeable and plasma fluids and proteins leakout,plasma protein attack bacteria and attract blood white cells.white blood cell engulf bacteria and help repair damage tissue

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