Monoclonal Antibodies in FLU Treatment

This animation illustrates how directing monoclonal antibodies to the influenza virus prevents a conformational change in the protein that is necessary for viral entry into the host cell.

Process

Monoclonal antibodies binds to the stem of Hemo gluttinin (HA) protein on the surface of the virus, virsus bind and engulfed by the cell, however this novel antibodies prevents the conformational change needed for the virus to fuse endosomal membrane and releases its viral RNA, this stops the viral life cycle and the virus is degraded.