Nonspecific Defenses- Fever

Fever is a frequent medical sign that describes an increase in internal body temperature to levels above normal.Fever is caused by an elevation in the thermoregulatory set-point, causing typical body temperature (generally and problematically considered to be 37 °C ±1 °C, or approximately 99 ±2 °F; see below for specifics) to rise, and effector mechanisms are enacted as a result. A feverish individual has a general feeling of cold despite an increased body temperature, and increases in heart rate, muscle tone and shivering, all of which are caused by the body's attempts to counteract the newly-perceived hypothermia and reach the new thermoregulatory set-point.

Fever is considered one of the body's immune mechanisms to attempt a neutralization of a perceived threat inside the body, be it bacterial or viral. Carl Wunderlich discovered that fever is not a disease, but the body's response to a disease.

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