How to Sequence a Genome

Animated and narrated segments presenting all the essential steps in sequencing a genome. From the NHGRI's Online Education Kit: Understanding the Human Genome Project.

Building Clone Libraries

Sub Clones

E. Coli Storage

Preparing DNA for Sequencing

Sequencing Reactions

Products of Sequencing Reactions

Separating the Sequencing Products

Reading the Sequencing Products

Assembling the Results

Working Draft Sequence


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