Maldi

Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization technique used in mass spectrometry, allowing the analysis of biomolecules (biopolymers such as...
Serotonin

The serotonin (5-hydroxytryptamine, 5-HT) receptors are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the...
Noradrenaline Animation

Noradrenaline (BAN) (abbreviated NA or NAd) or norepinephrine (INN) (abbreviated norepi or NE) is a catecholamine with dual roles as a...
How SSRIs and MAO Inhibitors Work Animation

Selective serotonin reuptake inhibitors or serotonin-specific reuptake inhibitor (SSRIs) are a class of compounds typically used as antidepressants in the treatment...
Bioenergetics
Bioenergetics is the subject of a field of biochemistry that concerns energy flow through living systems. This is an active area...
Mismeasure of Man
Ralph Horwitz, MD, professor of medicine at Stanford discusses how measurement can both strengthen and weaken clinical science and care. Often...
DNA Polymerase
DNA polymerase is an enzyme that catalyzes the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are best-known for their...
Elongation Factor EF-TU
EF-Tu (elongation factor thermo unstable) mediates the entry of the aminoacyl tRNA into a free site of the ribosome. EF-Tu functions...
Exploring the Mitochondria

A mitochondrion contains outer and inner membranes composed of phospholipid bilayers and proteins. The two membranes, however, have different properties. Because...
Zinc Finger Domain Animation
Zinc fingers are small protein domains that can coordinate one or more zinc ions to help stabilize their folds. They can...
Lysozyme Structure
Lysozymes, also known as muramidase or N-acetylmuramide glycanhydrolase, are a family of enzymes (EC 3.2.1.17) which damage bacterial cell walls by...
PPAR Inhibiors in Cancer Treatment
Poly (ADP-Ribose) Polymerase (PARP) is a protein cells use to repair genetic injuries naturally. But cancer cells also use this protein...
Alpha Helix

Alpha helix (α-helix) is a right- or left-handed coiled conformation, resembling a spring, in which every backbone N-H group donates a...
Photosystem I
Photosystem I is a proteinaceous transmembrane structure composed of several proteins and embedded with pigment molecules. This structure is located inside...
Cyclic Photophosphorylation
In cyclic electron flow, the electron begins in a pigment complex called photosystem I, passes from the primary acceptor to plastoquinone,...
Chemiosmotic phosphorylation
Chemiosmotic phosphorylation is the third pathway that produces ATP from inorganic phosphate and an ADP molecule. This process is part of...
Non-Cyclic Photophosphorylation
Non-cyclic photo- phosphorylation,cytochrome b6f uses the energy of electrons from PSII to pump protons from the stoma to the lumen. The...
Constitutive Secretion
In constitutive secretion Proteins are continuously secreted from the cell regardless of environmental factors. No external signals are needed to initiate...
Disulfide Bonds

Disulfide bonds play an important role in the folding and stability of some proteins, usually proteins secreted to the extracellular medium....
What is Mad Cow Disease

Bovine spongiform encephalopathy (BSE), commonly known as mad-cow disease (MCD), is a fatal, neurodegenerative disease in cattle, that causes a spongy...
Protein Recycling

Recycling is important not only on a global scale, but also at the cellular level, since key molecules tend to be...
Ribosome Ratchet

Comparison of two states of bacterial ribosome, either with fMet - tRNA bound or with elongation factor EF-G bound reveals the...
What is Polyribosome
Polyribosomes (or polysomes) are a cluster of ribosomes, bound to a mRNA molecule, first discovered and characterized by Jonathan Warner, Paul...
Laser Tweezers

An Laser tweezer is a scientific instrument that uses a focused laser beam to provide an attractive or repulsive force (typically...
How Depression is caused
Depression is one of the most common psychiatric disorders. Symptoms of depression are often subtle and unrecognized both by patients and...
Aspartate Transcarbamylase
Aspartate carbamoyltransferase (also known as ATCase or aspartate transcarbamoylase) catalyzes the first step in the pyrimidine biosynthetic pathway. Enzyme is a...
Proline Kinks
Integral membrane proteins often contain proline residues in their presumably alpha-helical transmembrane segments. This is in marked contrast to globular proteins,...
Glucose
Glucose (Glc), a monosaccharide (or simple sugar) also known as grape sugar, blood sugar, or corn sugar, is a very important...
Lymphocyte Homing
Lymphocyte "homing" process disperses the immunologic repertoire, directs lymphocyte subsets to the specialized microenvironments that control their differentiation and regulate their...
Neutrophil Chase

Neutrophils are white blood cells, which hunt and kill bacteria In this video neutrophil can be seen in the mist of...
Cytokine Signaling
Cytokines are a category of signaling molecules that are used extensively in cellular communication. They are proteins, peptides, or glycoproteins. The...
Lipids and Membranes
Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E...
Fluorescence Recovery After Photobleaching (FRAP)
Fluorescence recovery after photobleaching (FRAP) denotes an optical technique capable of quantifying the two dimensional lateral diffusion of a molecularity thin...
What is IgG Antibodies
Immunoglobulin G (IgG) is a monomeric immunoglobulin, built of two heavy chains γ and two light chains. Each IgG has two...
Lecture on Myoglobin and Hemoglobin
Myoglobin is a single-chain globular protein of 153 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around...
Uptake of Bacteria by Phagocytes
Uptake of bacteria by phagocytes is an active process, which requires triggering of specific receptors on phagocytes.Fc receptor, which binds antibody-coated...
Innate Recognition of Pathogens
In the initial stage of immune response, the innate immune system recognizes the presence of pathogens and provides the first line...
Induction of Apoptosis
Apoptosis in T cells and other cells can be activated through cell surface receptors called FAS,Fas are member of TNF receptor...
MAP kinase pathway, MAPK
The Mitogen activated Protein kinase pathway or MAP kinase pathway is a key signaling pathway by which cell responds to external...
Activated T Cell
In this video, we can see a T cell becomes activated when its interact with Dendritic cells (DCs).The T cell is...