Depression is one of the most common psychiatric disorders. Symptoms of depression are often subtle and unrecognized both by patients and physicians. The brain contains a network of interconnected nerve cells called neurons. The junction between the neurons is called the synaptic junction. Chemicals called neuro-transmitters facilitate the transmission of impulses from one neuron to another. The impulse triggers the release of neurotransmitters from one neuron, which cross the synaptic junction and attach themselves to the receptors in adjacent neurons sending the messages through.Later the neuro-transmitter returns to initial neuron the other reuptake channel.One of the causes of depressions believed to be the depletion of neuro transmitter called serotonin and noradrenaline.Antidepressant drugs increase the availability of neuro transmitters at the synaptic junction by blocking the re-uptake channel
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