Ribosome Ratchet

Comparison of two states of bacterial ribosome, either with fMet - tRNA bound or with elongation factor EF-G bound reveals the significant conformational change that ribosome thought to undergo during each elongation cycle, The Ratchet like rearrangement at interphase between two ribosomal sub unit may help to move the mRNa and tRna through the ribosome during protein synthesis

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